Fifteen years have passed since Joyce, Penny, and Fugi defeated Earl but they've kept in touch. Fugi continued her searches for an operation to reverse the sex-change, while Penny and Joyce
are happily married with good careers. Joyce is living a blissful life she never dreamt possible.
All of that is about to change.
Each of the fifteen years they've gathered in Cleveland Ohio to celebrate their victory.
Unbeknownst to them terrible forces have been watching and plotting revenge on a massive
scale, with a special interest in "The American Musketeers". They view the United States as their
enemy, one that must be annihilated. With an improved version of the character assassinating
drug from Earl, they've amassed an army more machine than human. Among their inductees are
US Armed Forces personnel unaware they are about to become pawns in a diabolical scheme. "It
commences with the repossession of three faulty units."