As civilization rapidly evolves into a new radical post-pandemic era, organizations and leaders need to adapt, innovate, and reimagine the future. This guidebook offers insights and strategies for leaders to thrive in this new era, empowering them to embrace their roles as Neo-Innovators, Neo-managers, and Neo-futurists. It is a concise "how-to" guide for anyone who is (or wants to be) involved in the development of radical innovations that solve problems and exploit opportunities in the post-pandemic world. Featuring actionable advice and examples from generative AI and the influencer culture to humanoid robots, self-driving cars and age-slowing therapies, this book equips young and experienced innovators, innovation leaders, and practitioners with the essential tools and mindset to tackle challenges and explore opportunities in a dynamic innovative landscape.