Missionary nuns named Sister Ruth and Sister Naomi, travel to St. Timothy's to undertake God's work, that was until the mission was overrun by Red Dog and the Hunters', a band of renegade Comanche Indians. They soon run across Arn Walker, a track and guide gunman, who offered the nuns protection only if they pledged to escort them to Helldorado. Arn ensembles the West's finest experts - Eb Tyler, a cowboy-turned-gunman, Mac Gibbs, an ex-Buffalo Soldier sergeant, and later Luke Brady, a drifter. After gunning their way through outlaws, and Apaches. The outlaws set their sights on the two sisters, believing they are the key to a vast fortune.