Protein Misfolding Diseases

ebook Advances in Protein Chemistry and Structural Biology

By Rossen Donev

cover image of Protein Misfolding Diseases

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Protein Misfolding Diseases, delves into the intricate molecular mechanisms behind a class of devastating disorders caused by abnormal protein folding. This comprehensive book explores the pathophysiology, diagnostic challenges, and therapeutic strategies associated with a spectrum of protein misfolding diseases, including neurodegenerative conditions like Alzheimer's, Parkinson's, and prion diseases, as well as systemic amyloidoses. From unraveling the underlying protein aggregation processes to discussing cutting-edge research on disease-modifying therapies, this book provides a multidisciplinary perspective on understanding and combating protein misfolding diseases. With contributions from leading experts in the field, it serves as a valuable resource for researchers, clinicians, and students seeking to deepen their knowledge of these complex and challenging disorders. - Provides a thorough examination of protein misfolding diseases, covering various types of disorders caused by aberrant protein folding - Explores the molecular mechanisms underlying protein misfolding and its implications on cellular function and disease progression - Focuses on specific protein misfolding disorders such as Alzheimer's disease, Parkinson's disease, prion diseases, and amyloidosis, offering in-depth insights into each condition
Protein Misfolding Diseases