Dry Eye Disease: A Clinical Handbook illuminates the translation of cutting-edge research on dry eye disease into practical situations, allowing clinical diagnosis and management of the condition using the latest evidence-based methods. It first presents research on the core pathophysiological features of dry eye disease, including tear film instability, hyperosmolarity, inflammation, and ocular surface damage. Thereafter, it champions a patient-centered approach to dry eye management, emphasizing the necessity of classifying the ocular surface disease(s) most relevant to each case. It discusses global disease distribution and the role of non-modifiable risk factors like age, sex, and ethnicity. Additionally, the book describes tools for monitoring symptoms over time and assessing subtle signs of the disease. Readers will find practical methods for improving patient outcomes both in clinical settings and at home. - Presents cutting-edge research on the pathophysiology of dry eye disease, including tear film instability, hyperosmolarity, inflammation and ocular surface damage - Translates new research to clinical practice, providing for patient diagnosis and management, in-office and at home - Emphasizes the importance of patient-centered care, with special attention on disease indicators and how they present differently