What's Thanksgiving without some challenge and adventure! Isaac and Joanie are off to visit their grandparents while trying to answer the question, "What are you really thankful for?". Along the way, they run into an oatmeal-loving friend, a skunk, a neighbor who is hard of hearing, and a rooster named Lucky. Through all that, Isaac discovers that he can be thankful for the challenges and difficult things...including the ones that come from thinking a little differently.