In the year since her near-fatal accident, ghost whisperer Elspeth Barclay has actively avoided spiritual trouble. Her sister invites Elle to a Halloween tour at a music museum, where she encounters a mournful spirit in search of her recently dead husband. Another guest on the tour keys in on Elle's interaction and hires her to identify an oddly protective ghost at her mansion.

When this second spirit expresses concern about the same "missing ghost" from the Halloween tour, Elle becomes aware of a dark shadow similar to those that caused her accident continuing to play pranks on her. Elle is drawn into a web of haunted histories, mischievous shadows, and a ghost-hunting team that needs her skills. As she unravels family rifts echoing through time, Elle must confront both playful spirits and her own fears. Together, she and the team must locate the relic that will free the missing spirit from its oppressive legacy.