Railroad baron Lew Preston fears his daughter Barbara might be kidnapped on her journey to marry his associate Jerry Crowther. So Savage, Pinkerton's toughest agent, is hired to escort her by rail from Chicago to California. The demure red-headed Barbara is soon revealed as a hellion. "Red" shows she can rough it when the train is wrecked, and she and Savage join a wagon travelling west. Then, a gang of crooks grab Red, and Savage risks his life in rescuing her. He realizes that Red is a reluctant bride, but doggedly continues west with the girl in tow. But on reaching Crowther in San Francisco, they are caught up in a maelstrom of treachery and torture. Has Savage completed his assignment only to find death?