In Wager Smart, Eddie and Uncle Mike take on a cold case for Arlene Adams, the wealthy widow of a notorious hitman. The case leads Eddie and his uncle to Vegas, where they meet the hitman's old partner, the Deacon, a legend in the mob. The cold case quickly spirals into an investigation of a current murder that requires the men to make a dangerous deal with the mob. Eddie's old girlfriend, a poker pro and sports betting insider, gives Eddie and his uncle an edge, but could also lure Eddie back into his old Vegas gambling habits. Eddie and his uncle must walk a fine line between the high rollers, mob business interests, competing crime syndicates and the police, to get justice.