The Zodiac Voyage is a continuation of The Journals of Uncle Hugo, a previous novel by Arend Wieman.

Once again Uncle Hugo goes on a space 'trip' around the Zodiac, but this time he's joined by a Celzod guru lady, also a follower of the Vi-Guru.

Together, with her expert knowledge and experience of the heavens, they encounter many different lives on many different planets. Often they face violence, vast mind power, innocence, wars, strange animals and a black magician. At one time almost poisoned to death, Uncle Hugo is nurtured to health again by his lady guru friend. On her home planet he is even learning to fly a small space vehicle.

After over two years of space travel, home again, they discover a deep love for each other.

One early morning Uncle Hugo experiences the presence and love of the Supreme Diety — he is God Realized! It is impossible to put into words.