Hell's Marshal Frank Butcher and his ragtag posse are back, this time wreaking havoc on the civilized east coast. Sent to bring back John Wilkes Booth and his gang before they can kill the current US President, Frank wrestles with what appears to be his destiny: killing innocent people. Equipped with a new gun that seems to enjoy killing, Frank struggles to keep himself under control. Meanwhile, Booth and his gang traverse his old stomping grounds, plotting to kill the president and re-start the civil war. Frank and his friends—with help from an unlikely place—have to stop Booth's plot, and keep Frank from losing himself in death.