Volume VI continues the development of the S_U1™ framework, a universal equation designed to model complex, chaotic systems across disciplines. Building on prior volumes, this work extends S_U1™ into eight new domains, including cancer, economics, dark matter, Alzheimer's, misinformation, and cosmic inflation—achieving predictive correlations between 95.6–96.2% under real-world conditions. The enhanced AC_Toy equation is validated using 2025 data, ensemble simulations, and feedback mechanisms, with further application to interplanetary timekeeping (The Cosmic Calendar). The volume includes mathematical appendices, domain-specific simulations in Python, a glossary, and proposed dynamic variables for future expansion (Volume VII).

Authored independently by N. Sahra, this volume is intended for interdisciplinary researchers, AI scientists, cosmologists, medical analysts, and systems theorists.