SET enables countries to enhance their veterinary services' capacities with specific, measurable, achievable, relevant and time-bound action plans.SET is used during a two-week in-country mission led by evaluators from FAO and the national focal points of veterinary services. These missions are designed to provide recommendations and action plans to improve countries' animal disease surveillance systems. This manual gives SET assessors a full mission breakdown as well as a step-by-step approach for making robust evaluations and precise recommendations.SET reveals the strengths and weaknesses of the assessed surveillance system, encompassing the country's institutional organization, laboratory operations, surveillance activities, epidemiologic surveillance workforce, data management, communications, and evaluation, all which are divided into 96 indicators in addition to ones for bioterrorism and agrocrime response under the SET Biothreat Detection Module. The SET Manual is an essential resource for any assessor in delivering objective, useful evaluations and ultimately strengthening countries' animal disease surveillance systems.